Sanford is an installation, video, and performance artist whose work has been exhibited worldwide, including at the Tate Britain and Tate Modern, the Whitney Museum of American Art, and the Studio Museum Harlem. He has participated in several national and international artist residencies, and has been a fellow in programs including the Socrates Sculpture Park Residency, the Lower Manhattan Cultural Council World Views AIR Program, and the P.S.1 International Studio Program. His numerous awards include a Creative Time Travel Grant, a Creative Capital Project Grant, a New York Percent for the Arts Commission, an Art Matters Grant, and a New York Foundation for the Arts Award.
A native of Los Angeles, Sanford received his MFA from the School of the Art Institute of Chicago. He has been on the faculty at Virginia Commonwealth Sculpture and Extended Media program.